Solvent free Synthesis of 2-[(5-methyl-1,3-benzoxazol-2-yl)sulfanyl] Acetohydrazide Derivatives as Novel Antimicrobial and Antitumor Agents
نویسندگان
چکیده
In pursuit of designing novel chemical entities with antitumor and antimicrobial activities, 2-[(5-methyl-1,3-benzoxazol-2-yl)sulfanyl]acetohydrazidederivatives have been synthesized as a scaffold series amine derivatives, these analogs were on reductive amination solvent free condition. All the compounds assessed for antibacterial, antifungal, activities against standard strains. The 3a, 3b 3g showed highest degree inhibition A. flavus 3b, 3d 3h Showed C. albicans, 3a,3e has shown encouraging antibacterial activityresults E. coli exhibited promising activity B. subtilis. Compounds 3c activity.
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ژورنال
عنوان ژورنال: Journal of pharmaceutical research international
سال: 2023
ISSN: ['2456-9119']
DOI: https://doi.org/10.9734/jpri/2023/v35i137368